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From157US$ /night
Check-in
16Nov2025Select date
Check-out
17Nov2025Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

1108 West Main Street, Durham, North Carolina, United States, 27701

Residence Inn By Marriott Durham Duke University Medical Center Area - All-suite hotel with indoor pool, full kitchens, and complimentary breakfast

Located in Downtown Durham, this 3-star Durham hotel features 147 air-conditioned suites with separate living, cooking, and sleeping areas. The Residence Inn provides apartment-style accommodations equipped with full kitchens including refrigerators, stovetops, and dishwashers. Each suite includes a private bathroom with a bath or shower, while select rooms offer additional seating areas. The property maintains an indoor heated pool and a 24-hour fitness center with cardio equipment and free weights. Five meeting venues spanning 2528 square feet accommodate business gatherings with AV equipment. Complimentary amenities include daily breakfast, WiFi, and on-site parking. The hotel sits 1 mile from Durham Bulls Athletic Park and 1.5 miles from Sarah P. Duke Gardens. A complimentary area shuttle service requires 24-hour advance reservations.

Pros

Complimentary reception events held on select days

Full-service business center with express check-in/out

Grocery delivery service available

Wedding services and event planning assistance

Cons

Area shuttle requires 24-hour advance booking

Located 15.5 miles from Raleigh-Durham International Airport

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Select your room type

Cozy rooms, spacious suites, and family-friendly homes, all with flexible cancellation policies & special deals
King Studio
2 persons
45 m² 
1 King-size bed
Coffee machine
Heating
Queen Studio Sofa Bed
2 persons
40 m² 
1 King-size bed
Coffee machine
Heating
One-Bedroom Suite
2 persons
44 m² 
1 King-size bed and 1 Sofa bed
Coffee machine
Heating
1 Bedroom Suite 1 King or 1 Queen Sofa bed Mobility Accessible w or Roll Shower
2 persons
39 m² 
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Getting around

Easily find local transportation options to help you explore

City Centre
Durham 1.5 km
Airports
Raleigh-Durham International (RDU) 25.0 km
Danville Regional (DAN) 91.6 km

Facilities

Enjoy premium amenities for a relaxing stay with your pet

General

  • No smoking on site
  • Free Wi-Fi
  • Parking
  • Safe deposit box
  • 24-hour reception
  • Express check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Security
  • Luggage storage
  • Lift
  • Fireplace
  • Smoke detectors
  • Fire extinguishers
  • Key card access
  • Key access

Sports & Fitness

  • Fitness centre

Guest Parking

  • Cookware/ Kitchen utensils

Services

  • Free shuttle service
  • Car hire
  • Laundry
  • Dry cleaning
  • Grocery shopping service
  • Shops/Commercial services

Dining

  • Bar/ Lounge area
  • Picnic area/ Tables

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Spa & Leisure

  • BBQ facilities
  • Leisure/ TV room

Room features

  • Air conditioning
  • Heating
  • Sitting area
  • Terrace
  • Garden furniture

Self-catering

  • Cookware/ Kitchen utensils
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Location

1108 West Main Street, Durham, North Carolina, United States, 27701
Map view
1108 West Main Street, Durham, North Carolina, United States, 27701
Nearby
Bridge
11 foot 8 Bridge
350 m
North Carolina Eye & Ear Hosp
130 m
Bridge
11'8"
350 m
Christian and Missionary Alliance Community Church
350 m
Church
Immaculate Conception Catholic Church
350 m
Duke University Museum of Art
540 m
Restaurants
Papa John's
200 m
1018 W Main St
Toast
960 m
345 West Main Street
King's Sandwich Shop
1.2 km
701 Foster Street
Cocoa Cinnamon
1.3 km
420 West Geer Street
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Check-in
16Nov2025Select date
Check-out
17Nov2025Select date
Rooms and Guests2 Guests, 1 Room