Save
up to 10%
when booking directly with us!
Check rooms and rates
From157US$ /night
Check-in
29Jun2025Select date
Check-out
30Jun2025Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

1108 West Main Street, Durham, North Carolina, United States, 27701

Residence Inn By Marriott Durham Duke University Medical Center Area - All-suite hotel with indoor pool, full kitchens, and complimentary breakfast

Located in Downtown Durham, this 3-star Durham hotel features 147 air-conditioned suites with separate living, cooking, and sleeping areas. The Residence Inn provides apartment-style accommodations equipped with full kitchens including refrigerators, stovetops, and dishwashers. Each suite includes a private bathroom with a bath or shower, while select rooms offer additional seating areas. The property maintains an indoor heated pool and a 24-hour fitness center with cardio equipment and free weights. Five meeting venues spanning 2528 square feet accommodate business gatherings with AV equipment. Complimentary amenities include daily breakfast, WiFi, and on-site parking. The hotel sits 1 mile from Durham Bulls Athletic Park and 1.5 miles from Sarah P. Duke Gardens. A complimentary area shuttle service requires 24-hour advance reservations.

Pros

Complimentary reception events held on select days

Full-service business center with express check-in/out

Grocery delivery service available

Wedding services and event planning assistance

Cons

Area shuttle requires 24-hour advance booking

Located 15.5 miles from Raleigh-Durham International Airport

View all

Select your room type

Cozy rooms, spacious suites, and family-friendly homes, all with flexible cancellation policies & special deals
King Studio
Max:
3 persons
485 sq. feet 
Bed options:
1 King-size bed
Coffee machine
Heating
Check Prices
Queen Studio Sofa Bed
Max:
3 persons
435 sq. feet 
Bed options:
1 King-size bed
Coffee machine
Heating
Check Prices
One-Bedroom Suite
Max:
3 persons
475 sq. feet 
Bed options:
1 King-size bed
Coffee machine
Heating
Check Prices
Show all roomsLess

Price and room availability calendar

Check availability and rates for your selected dates!

Getting around

Easily find local transportation options to help you explore

City Centre
Durham5000 ft
Airports
Raleigh-Durham International (RDU) 15.5 mi
Danville Regional (DAN) 56.9 mi

Facilities

Enjoy premium amenities for a relaxing stay with your pet

General

  • No smoking on site
  • Wi-Fi
  • Parking
  • Safe deposit box
  • 24-hour reception
  • Express check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Security
  • Luggage storage
  • Lift
  • Fireplace
  • Smoke detectors
  • Fire extinguishers
  • Key card access
  • Key access

Sports & Fitness

  • Fitness centre

Guest Parking

  • Cookware/ Kitchen utensils

Services

  • Free shuttle service
  • Car hire
  • Laundry
  • Dry cleaning
  • Grocery shopping service
  • Shops/Commercial services

Dining

  • Bar/ Lounge area
  • Picnic area/ Tables

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Spa & Leisure

  • BBQ facilities
  • Leisure/ TV room

Room features

  • Air conditioning
  • Heating
  • Sitting area
  • Terrace
  • Garden furniture

Self-catering

  • Cookware/ Kitchen utensils
Show more

Location

1108 West Main Street, Durham, North Carolina, United States, 27701
Map view
1108 West Main Street, Durham, North Carolina, United States, 27701
Nearby
Bridge
11 foot 8 Bridge
1200 ft
North Carolina Eye & Ear Hosp
500 ft
Bridge
11'8"
1200 ft
Christian and Missionary Alliance Community Church
1200 ft
Church
Immaculate Conception Catholic Church
1200 ft
Duke University Museum of Art
1800 ft
Restaurants
Papa John's
700 ft
1018 W Main St
Toast
3200 ft
345 West Main Street
King's Sandwich Shop
4100 ft
701 Foster Street
Cocoa Cinnamon
4200 ft
420 West Geer Street
Looking for exclusive early booking discounts?
Unlock special rates for your next adventure with your pet today!
Check Rates

Next best alternative

Consider them for your next trip.
Check-in
29Jun2025Select date
Check-out
30Jun2025Select date
Rooms and Guests2 Guests, 1 Room