21C Museum Hotel Louisville, Louisville

21C Museum Hotel Louisville - Contemporary Art Museum Hotel with Bourbon-Inspired Dining and Downtown Cultural Access

Located in historic Whiskey Row, this 5-star Louisville hotel combines a 9000-square-foot contemporary art museum with a 91-room boutique property. 21c Museum Hotel features soundproofed rooms equipped with flat-screen TVs, minibars, and coffee makers, while select accommodations offer premium Bryte Restorative Sleep Beds. The property houses Proof on Main restaurant, specializing in Ohio River Valley cuisine and maintaining one of the country's top-rated bourbon collections. Four private galleries accommodate events for 10 to 60 guests, with dedicated staff providing customized catering services. The hotel's exhibition spaces showcase rotating contemporary art installations and site-specific works. 21C Museum Hotel Louisville stands within a half-mile radius of the Kentucky Museum of Art & Craft, Frazier International History Museum, and Muhammad Ali Center. Guests can access the free ZeroBus two blocks away, connecting to downtown attractions including Slugger Field and Waterfront Park.

Pros

Houses an extensive bourbon collection through the 21c Selects Private Barrel Program

Hosts special events like Fork & Bottle dinner series featuring regional distillers

Preserves historical elements of former bourbon and tobacco warehouses

Offers immersive art experiences in specially designed guest rooms

Cons

Half-mile walk required to reach the Kentucky International Convention Center

Limited on-site parking options in downtown location