Save
up to 10%
when booking directly with us!
Check rooms and rates
From84US$ /night
Check-in
16Nov2025Select date
Check-out
17Nov2025Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

4100 W Shirley Place, Sioux Falls, South Dakota, United States, 57106-0707

Best Western Empire Towers - Interstate-adjacent hotel with indoor pool and business amenities

Located just off Interstate 29 Exit 396, this 3-star Sioux Falls hotel features 62 air-conditioned rooms equipped with flat-screen TVs, microwaves, and coffee makers. Best Western Empire Towers provides both an indoor heated pool and access to a nearby fitness facility. Each room includes a private bathroom with shower/tub combination, complimentary toiletries, and hair dryers. Business travelers have access to a business center, express check-in/out services, and complimentary wireless internet. The property serves a free full hot breakfast daily and includes a common area with television. Best Western positions guests 1 minute from Empire Mall and 6 minutes from Denny Sanford Premier Center. The hotel stands 9.5 miles from Sioux Falls Regional Airport, with attractions like the Great Plains Zoo and Delbridge Museum of Natural History within 2 miles.

Pros

Free airport shuttle service available

Multiple dining options within 1640.4 ft including Arby's, McDonald's, and Chili's

Convenient for medical visits with proximity to Avera Heart Hospital and Sanford Children's Hospital

Close to seasonal events like Jazz Fest and Hot Summer Nights in July

Cons

9.5 miles distance from airport

Fitness center located off-site

View all

Select your room type

Cozy rooms, spacious suites, and family-friendly homes, all with flexible cancellation policies & special deals
Queen Suite Non-Smoking
2 persons
22 m² 
1 King-size bed
Air conditioning
Queen Room Bath Tub Mobility Accessible or Non-Smoking
2 persons
22 m² 
1 King-size bed
Air conditioning
King Room Non-Smoking
2 persons
25 m² 
1 King-size bed
Air conditioning
Queen Room Roll Shower Mobility Accessible or Non-Smoking
2 persons
22 m² 
1 King-size bed
Air conditioning
Click button to see more rooms
Show all rooms
Show all roomsLess

Price and room availability calendar

Check availability and rates for your selected dates!

Getting around

Easily find local transportation options to help you explore

City Centre
Sioux Falls 4.3 km
Airports
Sioux Falls Regional (FSD) 13.7 km
Stronsay (soy) 94.3 km

Facilities

Enjoy premium amenities for a relaxing stay with your pet

General

  • No smoking on site
  • Free Wi-Fi
  • Parking
  • 24-hour reception
  • Express check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • 24-hour security
  • Lift
  • Vending machines
  • Smoke detectors
  • Fire extinguishers
  • Key card access

Services

  • Pet amenities available
  • Housekeeping

Dining

  • Special diet menus

Business

  • Business centre
  • Fax/Photocopying

Children

  • Cots
  • Children's buffet

Facilities for people with disabilities

  • Toilet for disabled
  • Bathroom for disabled

Spa & Leisure

  • Indoor swimming pool
  • Sun loungers
  • Leisure/ TV room

Room features

  • Air conditioning
  • Heating
  • Tea and coffee facilities
  • Ironing facilities

Media

  • AM/FM alarm clock
Show more

Location

4100 W Shirley Place, Sioux Falls, South Dakota, United States, 57106-0707
Map view
4100 W Shirley Place, Sioux Falls, South Dakota, United States, 57106-0707
Nearby
Casino
Empire Casino
330 m
Fireside Casino
380 m
Restaurants
Fazoli's
360 m
4224 West Empire Place
Wendy's
560 m
3701 W. 41st St.
Culver's
550 m
4001 W 41st St
Taco John's
470 m
4001 W 41st St
Agua Fresh
510 m
5000 W Empire Place Fc07
Slim Chickens
930 m
2711 S. Louise Ave.
Looking for exclusive early booking discounts?
Unlock special rates for your next adventure with your pet today!
Check Rates

Next best alternative

Consider them for your next trip.
Check-in
16Nov2025Select date
Check-out
17Nov2025Select date
Rooms and Guests2 Guests, 1 Room