Hampton Inn & Suites Orlando/Downtown South - Medical Center Fast Food photoHampton Inn & Suites Orlando/Downtown South - Medical Center Exterior photoHampton Inn & Suites Orlando/Downtown South - Medical Center Exterior photo
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From149US$ /night
Check-in
09Apr2026Select date
Check-out
10Apr2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

43 Columbia Street, Orlando, Florida, United States, 32806
-
Near the Medical Center
Great
8.9
9.2
/10
4.5
4.3
/5

Hampton Inn & Suites Orlando/Downtown South - Medical Center - A downtown hotel with free breakfast, outdoor pool, and business facilities

Located in Downtown Orlando amid modern office towers and 19th-century buildings, this 3-star Orlando hotel features 126 air-conditioned rooms with refrigerators and LCD televisions. Hampton Inn & Suites Orlando/Downtown South - Medical Center provides 1128 square feet of conference space with meeting rooms equipped with LCD projectors and conference phones. The property includes an outdoor pool and fitness center, while guest rooms feature either two queen or one king-sized Hampton clean and fresh beds, lap desks, and free WiFi. A complimentary hot breakfast buffet and Hampton's On the Run Breakfast Bags (Monday through Friday) serve morning diners, with a snack bar/deli available for other meals. The Hampton Inn positions guests within a 15-minute walk of Orange Avenue and walking distance to Arnold Palmer Hospital for Children. Landmark destinations within 1.5 miles include Camping World Stadium, Greenwood Urban Wetlands, and Downtown Orlando's farmers' market.

Pros

Pet-friendly accommodations accept two pets up to 75 pounds

Conference facilities include free WiFi and professional AV equipment

Safety features include carbon monoxide detectors, fire extinguishers, and first aid kits

Self-parking available with in/out privileges

Cons

Airport shuttle service not available

Valet parking not offered

“Hampton Inn & Suites Orlando/Downtown South wins points for its location near Orlando's medical district and walkable access to downtown. I especially note the practical perks, like gated parking and a generous breakfast, and the fact that it welcomes pets. For travelers seeking fuss-free convenience alongside their Hilton points, this property lands as a solid option.”
Hotel logo
Isabella MooreSenior Editorial Director at Petfriendlyhotels
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Select your room type

Cozy rooms, spacious suites, and family-friendly homes, all with flexible cancellation policies & special deals
King Room Hearing Accessible
2 persons
390 sq. feet 
1 King-size bed
Shower
Queen Room Two Queen Beds
2 persons
305 sq. feet 
2 King Size Beds
Shower
King Room
2 persons
360 sq. feet 
1 King-size bed
Shower
King Room Sofa Bed Non-Smoking
2 persons
370 sq. feet 
1 King-size bed and 1 Sofa bed
Shower
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Facilities

Enjoy premium amenities for a relaxing stay with your pet
Facilities: Perfect
9.1/10Review score

General

  • No smoking on site
  • Wi-Fi
  • Parking
  • Safe deposit box
  • 24-hour reception
  • VIP check-in/ -out
  • Express check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Security
  • Luggage storage
  • Lift
  • Vending machines
  • Smoke detectors
  • Fire extinguishers
  • Key card access

Sports & Fitness

  • Fitness centre

Services

  • Housekeeping
  • Laundry
  • Dry cleaning
  • Shops/Commercial services
  • Welcome drink

Dining

  • Snack bar

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Children

  • Children's buffet

Spa & Leisure

  • Outdoor swimming pool
  • Sun loungers
  • Leisure/ TV room

Room features

  • Air conditioning
  • Heating
  • Sitting area
  • Garden furniture
  • Tea and coffee facilities
  • Ironing facilities

Media

  • Flat-screen TV
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Hampton Inn & Suites Orlando/Downtown South - Medical Center Location

43 Columbia Street, Orlando, Florida, United States, 32806
Map view
43 Columbia Street, Orlando, Florida, United States, 32806
Nearby
Amusement Park
Delaney Street Playground
1800 ft
Hospital
Orlando Regional Medical Center
1000 ft
Orlando Regional-Lucerne
1500 ft
Hospital
Winnie Palmer Hospital for Women and Babies
1900 ft
Restaurants
Delaney's Tavern
1500 ft
1315 S Orange Ave
Lucy Bleuz Cafe
1800 ft
1321 Sligh Blvd
Incredibly Edible
1800 ft
1321 Sligh Blvd
Orlando Brewing
2200 ft
1301 Atlanta Avenue
Brick & Fire
2600 ft
1621 S Orange Ave Ste 108
Pizza Hut
2600 ft
1621 S Orange Ave
Subway
3200 ft
1742 S Orange Ave
7-Eleven
3500 ft
1823 S Orange Ave
Explore Orlando
Explore Nearby Orlando
Top Attractions
Activities
Dining
Entertainment
Orange County Regional History Center
20 minutes' walk
Historical exhibits showcasing Orlando's past. Ideal for families and history buffs, with guided tours available.
Lake Eola Park
30 minutes' walk
A picturesque park featuring a lake, swan boats, and walking trails. Perfect for leisurely strolls or picnics.
Downtown Orlando
25 minutes' walk
Vibrant area with shops, dining, and nightlife. A hub for culture and entertainment, suitable for all ages.
Outdoor Yoga Classes
30 minutes' walk
Relaxing yoga sessions at Lake Eola Park. Great for all skill levels and a refreshing way to unwind.
Adventure Park
10-minute drive
Thrilling zip-lining and obstacle courses. Perfect for thrill-seekers; reservations recommended.
Delaney's Tavern
6 minutes' walk
Casual eatery known for its craft beers and wings. Warm atmosphere and extensive menu catering to various diets.
Lucy Bleuz Cafe
7 minutes' walk
Charming café featuring American cuisine with an emphasis on freshness. Offers vegetarian options and homemade desserts.
Dr Phillips Center for the Performing Arts
20 minutes' walk
A premier venue for concerts and shows. Family-friendly events and rotating performances keep visits exciting.
Mad Cow Theatre
20 minutes' walk
Intimate theater hosting captivating plays. Offers a mix of modern and classic performances suitable for all audiences.
Getting around
City Centre
Orlando6 min  ·  1700 ft
Airports
Orlando Executive (ORL)12 min  ·  4.7 mi
Orlando International (MCO)28 min  ·  11.2 mi
Train
Church Street Station16 min  ·  4300 ft
Woodsmere Sub-Station15 min  ·  5.8 mi
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Property information and rules
Check-in
from 15:00-23:59
Check-out
until 11 am
Guest Parking
Private parking is possible on site (reservation might be needed) at USD 18 per day.
Internet
Wireless internet is available in for free.
Breakfast
All visitors are offered a buffet breakfast for a fee. 
Children & extra beds
There are no cots provided in a room. 
Pets
Pets are allowed on request.
Languages
Spanish
Number of floors:
6
Number of rooms:
126

Reviews and Ratings

Feedback about Hampton Inn & Suites Orlando/Downtown South - Medical Center from previous guests about their experience.
Review score
Based on 500 verified reviews
9.0/10
Perfect
92%
Recommend
Cleanliness
9.2/10
Comfort
9.1/10
Facilities
9.1/10
Free Wi-Fi
9.0/10
Location
8.9/10
Staff
9.2/10
Value for money
8.6/10
Pros
Comfy bed
Good location
Helpful staff
Fantastic breakfast
Cons
Transportation issues
Non-working TV
Guest reviews
based on 689 reviews
8.9/10
No reviews yet on our siteUnfortunately, our guests have not yet left any reviews for this hotel, but you can read reviews from Booking.com.
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FAQs
About Hampton Inn & Suites Orlando/Downtown South - Medical Center
What time is check-in and check-out at Hampton Inn & Suites Orlando/Downtown South - Medical Center?
Check-in is at 15:00 and check-out is by 11:00.
How far is Hampton Inn & Suites Orlando/Downtown South - Medical Center from Orlando Executive Airport?
The hotel is located 5 km from Orlando Executive Airport.
What amenities are available in the rooms at Hampton Inn & Suites Orlando/Downtown South - Medical Center?
Rooms include air conditioning, a flat-screen TV, a mini-refrigerator, and coffee-making facilities.
Is breakfast available at Hampton Inn & Suites Orlando/Downtown South - Medical Center?
A complimentary continental breakfast is served daily.
What recreational facilities does Hampton Inn & Suites Orlando/Downtown South - Medical Center offer?
Guests can enjoy an outdoor swimming pool and a fitness center.
Does Hampton Inn & Suites Orlando/Downtown South - Medical Center have on-site parking?
Private parking is available on-site for 18 USD per day, and reservation is needed.
What are some nearby attractions to Hampton Inn & Suites Orlando/Downtown South - Medical Center?
Nearby attractions include Orange Avenue (2 km), Amway Center (1 km), and the Wizarding World of Harry Potter(TM).
What business facilities are available at Hampton Inn & Suites Orlando/Downtown South - Medical Center?
The hotel offers a business center and meeting space with audio-visual equipment.
What languages are spoken by the staff at Hampton Inn & Suites Orlando/Downtown South - Medical Center?
The staff speaks English.
Is there a convenience store or snack bar at Hampton Inn & Suites Orlando/Downtown South - Medical Center?
Yes, there is a snack bar/deli available on-site.
How far is Hampton Inn & Suites Orlando/Downtown South - Medical Center from the city center?
The hotel is situated about 2 km from the city center of Orlando.
What options are available for late check-out at Hampton Inn & Suites Orlando/Downtown South - Medical Center?
Late check-out is available where possible.

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Check-in
09Apr2026Select date
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Rooms and Guests2 Guests, 1 Room