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From139US$ /night
Check-in
16Dec2025Select date
Check-out
17Dec2025Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

120 Shinn Lane, Hannibal, Missouri, United States
-
Near the Mark Twain Memorial Lighthouse
Perfect
9.2
9.7
/10
4.9
/5

Holiday Inn Express & Suites - Hannibal - Medical Center - A modern 3-star hotel with indoor heated pool, fitness center, and complimentary breakfast

Located just off Interstate 36 at the Shinn Lane exit, this 3-star Hannibal hotel features 83 air-conditioned rooms with free WiFi, HDTV, and spacious upgraded bath amenities. The comfortable accommodations include 42-inch flat-screen TVs, microwaves, refrigerators, and enhanced bed linens with bedside outlets and plush duvets. Guests at the Holiday Inn Express start each day with a complimentary Express Start Breakfast served from 6:30 AM, offering a delicious array of hot and cold favorites. For leisure, visitors can take advantage of the heated indoor pool open from 6:00 AM to 10:00 PM, fitness facility with treadmills and free weights, and guest laundry services. Business travelers benefit from laptop-friendly workspaces, a business center, and meeting space that can accommodate up to 80 people in the 1080-square-foot Tom Sawyer Room. Situated within walking distance of Hannibal Regional Hospital and the James E Cary Cancer Center, the property is also near major companies including BASF Corporation, Continental Cement, and General Mills.

Pros

Walking distance to medical facilities including Hannibal Regional Hospital and Hannibal Clinic

Convenience market and quick snacks available in The Market

18 suite rooms available among the 83 total accommodations

Located just 31.1 miles from Quincy Regional Airport

Pet-friendly policy allows service animals

Cons

Historic downtown attractions require a short car ride from the hotel

Airport shuttle service is not available from Louis Lambert International Airport

“Holiday Inn Express & Suites in Hannibal emphasizes cleanliness, even using bedbug-proof mattress covers, which is a definite plus for peace of mind. The hotel's location near the Hannibal Regional Hospital makes it especially convenient, and the indoor pool is a nice touch for year-round relaxation. I think it's a solid choice for both business and family trips.”
Hotel logo
James DavidEditor-in-Chief at Petfriendlyhotels
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Select your room type

Cozy rooms, spacious suites, and family-friendly homes, all with flexible cancellation policies & special deals
Suite Two Beds Non-Smoking
5 persons
Bathtub
Air conditioning
Standard Room
3 persons
Bathtub
Air conditioning
Queen Room Two Queen Beds Mobility Access Tub or Non-Smoking
4 persons
Bathtub
Air conditioning
King Room Hearing Accessible Non-Smoking
3 persons
Bathtub
Air conditioning
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Facilities

Enjoy premium amenities for a relaxing stay with your pet

General

  • Non-smoking property
  • Free internet access
  • Parking
  • Safe deposit box
  • 24-hour reception
  • Pets allowed
  • Wheelchair access
  • Air conditioning in public areas
  • ATM/Cash machine
  • Sundry/Convenience shop
  • Gift/Newsstand

Sports & Fitness

  • Fitness centre
  • Golf course

Services

  • Laundry

Dining

  • Restaurant

Spa & Leisure

  • Indoor swimming pool
  • Casino

Room features

  • Free Wi-Fi in rooms
  • In-room safe

Media

  • Flat-screen TV
  • Direct dial telephone
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Location

120 Shinn Lane, Hannibal, Missouri, United States
Map view
120 Shinn Lane, Hannibal, Missouri, United States
Restaurants
Subway
140 m
100 Shinn Lane
Mimi's Coffehouse and Ice Cream
830 m
106 Lakeside Dr
Explore Hannibal
Local Highlights
Top Attractions
Activities
Dining
Entertainment
Mid-America Aviation Inc
25 minutes' walk
Aviation museum showcasing aircraft and aviation history. Great for enthusiasts and families, features special exhibits.
Huck Finn Shopping Center
45 minutes' walk
Shopping center with diverse retail options. Perfect for families and couples looking for local shops and dining.
Rockcliffe Mansion
15-minute drive
Historic mansion offering tours. Known for its architecture and gardens, making it a unique spot for history lovers.
Mark Twain Statue
15-minute drive
Iconic statue honoring the famous author Mark Twain. A must-see for literature fans and great for photos.
Norwoods Golf Course
10-minute drive
Challenging golf course for enthusiasts. Featuring a scenic layout suitable for all skill levels, club rentals available.
Huckleberry Park
50 minutes' walk
Spacious park ideal for picnics and walks. Features playgrounds and trails, perfect for families and those seeking relaxation.
Subway
5 minutes' walk
Casual fast-food with fresh sandwiches. Ideal for quick meals, offering vegetarian options and customizable choices.
Mimi's Coffeehouse and Ice Cream
10 minutes' walk
Charming cafe with coffee and homemade ice cream. Family-friendly atmosphere, perfect for a sweet treat after a day out.
Hannibal's Historic Main Street
15-minute drive
Vibrant area with shops, dining, and occasional live performances. Great for families and couples seeking evening outings.
Local Bars and Pubs
15-minute drive
Several venues offer nightlife options, including live music. Ideal for solo travelers seeking a local vibe or lively atmosphere.
Getting around
City Centre
Hannibal11 min  ·  7.3 km
Airports
Quincy Regional Airport (UIN)75 min  ·  49.7 km
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Property information and rules
Check-in
from 15:00-23:59
Check-out
until 12 pm
Guest Parking
Public parking is possible on site for free.
Internet
Wireless internet is available in the hotel rooms for free.
Children & extra beds
There are no extra beds provided in a room. 
Pets
Pets are not allowed.
Number of floors:
4
Number of rooms:
83
FAQs
About Holiday Inn Express & Suites - Hannibal - Medical Center
What are the check-in and check-out times at Holiday Inn Express & Suites - Hannibal - Medical Center?
Check-in is from 15:00 and check-out is by 12:00.
What dining options are available at Holiday Inn Express & Suites - Hannibal - Medical Center?
The hotel offers a complimentary buffet breakfast and features an on-site convenience market for snacks and drinks.
Is parking available at Holiday Inn Express & Suites - Hannibal - Medical Center?
Free parking services are provided at the hotel.
What amenities are provided in the rooms at Holiday Inn Express & Suites - Hannibal - Medical Center?
Rooms include air conditioning, free Wi-Fi, a flat-screen TV, and microwave and refrigerator for added convenience.
Is there a pool at Holiday Inn Express & Suites - Hannibal - Medical Center?
Guests can enjoy a heated indoor pool for relaxation.
Which attractions are near Holiday Inn Express & Suites - Hannibal - Medical Center?
Nearby attractions include Mark Twain Cave (approximately 5 km), Historic Downtown Hannibal (approximately 5 km), and Mark Twain Boyhood Home and Museum (approximately 5 km).
What is the distance from Holiday Inn Express & Suites - Hannibal - Medical Center to Quincy Regional Airport?
The hotel is 50 km from Quincy Regional Airport.
What fitness facilities are available at Holiday Inn Express & Suites - Hannibal - Medical Center?
Guests have access to a 24-hour fitness center.
Does Holiday Inn Express & Suites - Hannibal - Medical Center provide business services?
The hotel features a business center equipped with printing and office supplies.

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