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From143US$ /night
Check-in
31Dec2025Select date
Check-out
01Jan2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

1528 Locust Street, Saint Louis, Missouri, United States, 63103
-
Steps from the City Museum
Great
8.5
8.9
/10
4.2
4.2
/5

21C Museum Hotel St Louis - A Downtown Art Hotel with Historic Indoor Pool and Contemporary Gallery Space

Located in Downtown St Louis district, this 4-star Saint Louis hotel occupies a historic building that once served as a YMCA. The property features a 4-lane lap pool, sauna, steam rooms, and a 24-hour fitness center at the Locust Street Athletic and Swim Club. Guest accommodations include air-conditioned rooms and suites equipped with flat-screen TVs, streaming services, seating areas, and private bathrooms with walk-in showers. The two-story 21c King Suite offers a fireplace, kitchenette, and personal fitness loft. Idol Wolf restaurant serves Spanish-inspired tapas using local ingredients. The property houses a contemporary art museum with rotating exhibitions, open 24/7 and free to visitors. Located 1640.4 ft from Christ Church Cathedral, 21C Museum Hotel places guests 1 mile from Busch Stadium and 1 mile from the Gateway Arch.

Pros

Free 24/7 access to contemporary art exhibitions and installations

Historic indoor pool with sauna and steam rooms

Spanish tapas restaurant blending Iberian and Midwestern flavors

Personal training and group fitness classes available

Cons

30.5 miles from Six Flags Over Mid-America

21 mile from Hollywood Casino St Louis

“I see a commitment to artful hospitality at this property, most visibly through its integration of contemporary installations and exhibitions. The indoor pool and wellness offerings, along with innovative dining, stand out as key amenities in the Downtown St Louis location. For travelers seeking a blend of culture and comfort, it presents a distinctive option.”
Hotel logo
Isabella MooreSenior Editorial Director at Petfriendlyhotels
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Select your room type

Cozy rooms, spacious suites, and family-friendly homes, all with flexible cancellation policies & special deals
Deluxe King Room
2 persons
29 m² 
1 King-size bed
Shower
Heating
Deluxe King Suite Roll Shower Accessible
2 persons
47 m² 
1 King-size bed
Shower
Heating
Loft Two Queen Beds
2 persons
40 m² 
2 King Size Beds
Shower
Heating
Deluxe King Room Accessible
2 persons
29 m² 
1 King-size bed
Shower
Heating
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Facilities

Enjoy premium amenities for a relaxing stay with your pet

General

  • No smoking on site
  • Wi-Fi
  • Safe deposit box
  • 24-hour reception
  • VIP check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • 24-hour security
  • Luggage storage
  • Locker room
  • Allergy-free rooms
  • Lift
  • ATM/Cash machine
  • Coffee shop
  • Vending machines
  • Smoke detectors
  • Fire extinguishers
  • Key card access

Sports & Fitness

  • Fitness centre
  • Billiard tables
  • Yoga class

Services

  • Valet parking
  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Welcome drink

Dining

  • Restaurant
  • Bar/ Lounge area
  • Special diet menus

Business

  • Business centre
  • Meeting/ Banquet facilities

Children

  • Cots
  • Board games
  • Game room

Facilities for people with disabilities

  • Toilet for disabled

Spa & Leisure

  • Indoor swimming pool
  • Leisure/ TV room
  • Spa & wellness centre
  • Steam room
  • Jacuzzi
  • Massage

Room features

  • Air conditioning
  • Heating
  • Soundproofed rooms
  • Sitting area
  • Terrace
  • Garden furniture
  • Ironing facilities

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
  • Direct dial telephone
  • AM/FM alarm clock
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Location

1528 Locust Street, Saint Louis, Missouri, United States, 63103
Map view
1528 Locust Street, Saint Louis, Missouri, United States, 63103
Nearby
Museum
City Museum
520 m
Museum
Campbell House Museum
90 m
Church
Christ Church Cathedral
430 m
1315 Chestnut St
Soldiers Memorial Military Museum
590 m
Aquarium
World Aquarium
400 m
Church
Centenary United Methodist Church
190 m
Night club
The Boom Boom Room
280 m
13th and Locust
Lucas Garden Park
350 m
Restaurants
The Last Kitchen
360 m
1501 Washington Ave Inside The Last Hotel
Red Oak Biscuits
310 m
1330 Washington Ave
Nara Cafe and Hookah Lounge
310 m
1326 Washington Ave
Flannery's
380 m
1324 Washington Ave
Rooftop Cafe at City Museum
400 m
701 N 15th St Fl 11
Lucas Park Grille
440 m
1234 Washington Avenue
Rosalita's Cantina
480 m
1235 Washington Avenue
Blondie's Coffee
450 m
1301 Washington Ave
Imo's Pizza
410 m
1828 Washington Ave
Papa John's Pizza
610 m
201 N Tucker Blvd Ste E
Bootleggin' BBQ
650 m
1933 Washington Ave
Explore Saint Louis
Explore St. Louis
Top Attractions
Activities
Dining
Entertainment
City Museum
City Museum
5 minutes walking
A whimsical blend of playground and art installation, featuring slides and tunnels alongside engaging exhibits.
Campbell House Museum
Campbell House Museum
2 minutes walking
A historic house museum showcasing 19th-century art and furnishings in a beautifully preserved setting.
Kiener Plaza
Kiener Plaza
8 minutes walking
A vibrant public park with sculptures and fountains, perfect for a leisurely stroll or a quick lunch break.
The Gateway Arch
The Gateway Arch
25 minutes walking
Iconic monument symbolizing westward expansion, featuring sweeping views from its peak and a visitor center.
Bike Rentals at Citygarden
15 minutes walking
Bike rentals available in Citygarden, offering a fun way to explore the beautiful downtown area.
Yoga at the Park
8 minutes walking
Outdoor yoga classes held in nearby parks, perfect for relaxation and connecting with nature.
Thrill Rides at Six Flags
30 minutes driving
Amusement park famous for its adrenaline-pumping roller coasters and family-friendly attractions.
The Last Kitchen
The Last Kitchen
5 minutes walking
An eclectic menu with locally sourced ingredients offering a casual and inviting atmosphere.
Flannery's
Flannery's
5 minutes walking
Irish pub known for hearty comfort food and a great selection of beers in a lively setting.
Rooftop Cafe at City Museum
Rooftop Cafe at City Museum
5 minutes walking
Offers stunning views of the city alongside a casual dining experience with diverse menu options.
Stifel Theatre
Stifel Theatre
8 minutes walking
Home to a variety of performances including concerts and comedy shows, in a historic and beautiful venue.
National Blues Museum
National Blues Museum
16 minutes walking
A tribute to the history of blues music with interactive exhibits and frequent live performances.
Live Jazz at The Last Kitchen
5 minutes walking
Enjoy live jazz performances in a relaxed atmosphere, a highlight for music lovers and visitors alike.
Getting around
City Centre
Saint Louis8 min  ·  600 m
Airports
St. Louis Lambert International Airport (STL)33 min  ·  21.8 km
Belleville, IL (BLV)62 min  ·  40.8 km
Train
Union Station9 min  ·  700 m
Bus
Bus stop3 min  ·  200 m
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Property information and rules
Check-in
from 16:00-23:59
Check-out
until 11 am
Guest Parking
No parking available.
Internet
is available in for free.
Pets
Pets are allowed on request.
Number of floors:
10
Number of rooms:
137
FAQs
About 21C Museum Hotel St Louis
What is the distance from 21C Museum Hotel St Louis to St Louis Lambert International Airport?
The hotel is located 21 km from St Louis Lambert International Airport.
What room amenities are available at 21C Museum Hotel St Louis?
Rooms feature air conditioning, a flat-screen TV, a seating area, a safety deposit box, and a private bathroom with free toiletries.
What indoor activities are available at 21C Museum Hotel St Louis?
Guests can enjoy activities such as billiards and access to a games room.
Is breakfast provided at 21C Museum Hotel St Louis?
An American breakfast is available for guests at the hotel.
What wellness facilities does 21C Museum Hotel St Louis offer?
The hotel features a spa and wellness center, an indoor swimming pool, and a hot tub.
How far is 21C Museum Hotel St Louis from popular attractions like the Gateway Arch?
The hotel is approximately 3 km from the Gateway Arch.
What dining options are available on-site at 21C Museum Hotel St Louis?
The hotel offers an à la carte restaurant serving Spanish cuisine and a lounge bar for drinks.
What are the check-in and check-out times at 21C Museum Hotel St Louis?
Check-in time is at 16:00 and check-out time is at 11:00.
What business services are offered at 21C Museum Hotel St Louis?
The hotel provides meeting and event spaces with advanced AV technology.
Is Wi-Fi available at 21C Museum Hotel St Louis?
Complimentary Wi-Fi is available throughout the property.
What is the policy for parking at 21C Museum Hotel St Louis?
Valet parking service is available for guests at the hotel.

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