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From251US$ /night
Check-in
31Dec2025Select date
Check-out
01Jan2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

167 West Main Street, Lexington, Kentucky, United States, 40507
-
Close to Triangle Park
Great
8.2
8.7
/10
4.5
4.2
/5

21C Museum Hotel Lexington - A contemporary art museum hotel in a historic bank building with rotating exhibitions and chef-driven dining

Located in downtown's historic Fayette National Bank Building, this arts-focused Lexington hotel showcases over 7000 square feet of exhibition space featuring rotating contemporary artworks and site-specific installations. The McKim, Mead and White-designed property, renovated by Deborah Berke Partners, offers rooms with custom furnishings, Malin + Goetz amenities, and original artwork. 21C Museum Hotel Lexington's Lockbox restaurant sources ingredients from local Kentucky providers, with menus that change seasonally. Meeting facilities include one conference room for 12 people and five private galleries accommodating 10-100 guests, while the Main Gallery hosts up to 250 for receptions. The property provides 24-hour valet service, a business center, and laundry facilities. 21C Museum Hotel sits at the intersection of Main Street's dining and cultural attractions, with Rupp Arena and the Convention Center just 0.5 miles away.

Pros

Free guided art tours available of the rotating exhibitions and permanent installations

Historic bank vault converted into unique private dining space

Pet-friendly rooms with no fees in 2022

Local partnerships with Kentucky bourbon distilleries offering exclusive private barrel selections

Cons

9.5 miles from Blue Grass Airport

Limited on-site parking with valet-only option at $30 per night

“21c Museum Hotel Lexington impresses with its dedication to contemporary art, seamlessly integrated throughout a historic building in downtown Lexington. Lockbox, the hotel restaurant, earns high marks, particularly for its brunch, and the hotel's commitment to sustainability and local sourcing is a welcome touch. While some rooms show signs of wear, the hotel's unique character and friendly staff ultimately create a memorable stay.”
Hotel logo
Isabella MooreSenior Editorial Director at Petfriendlyhotels
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Select your room type

Cozy rooms, spacious suites, and family-friendly homes, all with flexible cancellation policies & special deals
City Queen Room
2 persons
22 m² 
1 King-size bed
Shower
Coffee machine
Deluxe Queen Room
2 persons
33 m² 
2 King Size Beds
Shower
Coffee machine
Deluxe King Room
2 persons
31 m² 
1 King-size bed
Shower
Coffee machine
Corner King Room
2 persons
40 m² 
1 King-size bed
Shower
Coffee machine
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Price and room availability calendar

Check availability and rates for your selected dates!

Facilities

Enjoy premium amenities for a relaxing stay with your pet

General

  • No smoking on site
  • Free Wi-Fi in public areas
  • Safe deposit box
  • 24-hour reception
  • VIP check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • 24-hour security
  • Luggage storage
  • Allergy-free rooms
  • Lift
  • ATM/Cash machine
  • Vending machines
  • Smoke detectors
  • Fire extinguishers
  • Key card access
  • Key access

Sports & Fitness

  • Fitness centre
  • Yoga class

Services

  • Paid shuttle service
  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Tours/Ticket assistance
  • Welcome drink

Dining

  • In-room breakfast
  • Restaurant
  • Snack bar
  • Bar/ Lounge area
  • Special diet menus

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Children

  • Children's menu

Room features

  • Air conditioning
  • Heating
  • Soundproofed rooms
  • Sitting area
  • Dressing area
  • Tea and coffee facilities
  • Dining table
  • Ironing facilities

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
  • AM/FM alarm clock
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Dining Onsite

At 21C Museum Hotel Lexington, guests can savor enticing dining experiences at Lockbox, where local American cuisine meets flexible dining options, ensuring authenticity and satisfaction with every bite. Whether starting the day with a hearty breakfast or unwinding over dinner, the flavors are sure to delight any palate.
21C Museum Hotel Lexington Restaurant photo

Lockbox

American, Local
Ambiance
A contemporary space that invites guests to relax and indulge in a warm and welcoming atmosphere.
Key Offerings
The menu features vibrant dishes that cater to various dietary preferences, including vegetarian, vegan, gluten-free, and dairy-free options. Breakfast and dinner selections are thoughtfully crafted to showcase local flavors.
Reservation
Recommended for dinner.
Open for breakfast from 7:00 AM - 11:00 AM (Wednesday to Saturday) and dinner from 5:00 PM - 10:00 PM (Wednesday to Thursday), 5:00 PM - 11:00 PM (Saturday), and 5:00 PM - 9:00 PM (Sunday).

Red River Rockhouse

Café
Ambiance
A family-owned café that exudes a cozy, home-like feel, perfect for unwinding with a coffee or a casual meal.
Key Offerings
Focused on sustainability, this café serves hearty dishes crafted from locally sourced ingredients, making it an ideal stop for those seeking authentic, wholesome food.
Reservation
Not needed.
Hours vary; please check locally.

La Cabana Mexican Restaurant

Mexican
Ambiance
Casual and vibrant, transporting guests to the heart of Mexico with colorful decor and a lively atmosphere.
Key Offerings
Indulge in mouthwatering burritos and refreshing margaritas, ideal for those looking to relax and savor traditional Mexican flavors.
Reservation
Not needed.
Hours vary; please check locally.

Miguel's Pizza

Pizza
Ambiance
Fun and laid-back, this pizzeria has a rustic charm that invites diners to enjoy a slice in a friendly environment.
Key Offerings
Famous for its delicious pizza, Miguel's is a must-visit for guests seeking a casual dining experience with a local twist.
Reservation
Not needed.
Hours vary; please check locally.

Location

167 West Main Street, Lexington, Kentucky, United States, 40507
Map view
167 West Main Street, Lexington, Kentucky, United States, 40507
Nearby
430 West Vine Street
Rupp Arena
460 m
Museum
Hunt-Morgan House
460 m
Event hall
Lexington Convention Center
440 m
Theatre
Kentucky Theatre
360 m
440 W Short St
Explorium
450 m
University
University of Kentucky
90 m
Park
Triangle Park
340 m
Church
St Paul the Apostle Catholic Church
430 m
Library
Lexington Public Library Ceiling Clock and Foucault Pendulum
260 m
Shopping Area
Victorian Square Shoppes
340 m
Square
Phoenix Park
180 m
Gallery
Limestone Blue
130 m
Lexington Financial Center
Isaac Murphy Memorial Art Garden
140 m
Gallery
Pam Miller Downtown Arts Center
220 m
Gallery
ArtsPlace
240 m
7285 Huron Street
Huron Street Gallery
250 m
Gratz Park
490 m
Restaurants
Bourbon on Rye
70 m
115 W Main St
Corto Lima
180 m
101 West Short Street Corner of West Short and North Limestone Streets
School Sushi
120 m
163 West Short Street
Bluegrass Tavern
150 m
115 Cheapside
Horse And Jockey
190 m
131 Cheapside
Buddha Lounge
190 m
109 N Mill St
Explore Lexington
Local Highlights
Top Attractions
Activities
Dining
Entertainment
Rupp Arena
Rupp Arena
6 minutes' walk
Home of the Kentucky Wildcats, this venue hosts sports events and concerts throughout the year with a lively atmosphere.
Mary Todd Lincoln House
Mary Todd Lincoln House
9 minutes' walk
The childhood home of Mary Todd Lincoln, showcasing fascinating exhibits on the Civil War era and Lincoln's life.
University of Kentucky Art Museum
University of Kentucky Art Museum
13 minutes' walk
Features a mix of Southern and contemporary art in a serene setting, with free admission days promoting accessibility.
Explorium
Explorium
6 minutes' walk
A hands-on children's museum with interactive exhibits, perfect for families looking to engage kids with learning through play.
Lexington Greenway Trail
10 minutes' drive
A scenic trail ideal for biking or walking, perfect for those seeking outdoor adventure amid beautiful landscapes.
The Arboretum
10 minutes' drive
A tranquil garden where visitors can relax, featuring walking trails and seasonal plant displays; open year-round.
Bourbon on Rye
Bourbon on Rye
1 minute' walk
A lively spot offering southern comfort food and an extensive bourbon selection, perfect for casual dining and gatherings.
Corto Lima
Corto Lima
3 minutes' walk
Latin-inspired dishes in a vibrant setting, known for its tacos and fresh margaritas; vegetarian options available.
School Sushi
School Sushi
2 minutes' walk
A relaxed eatery specializing in sushi with creative rolls; popular among locals for its fresh products and casual vibe.
Kentucky Theatre
Kentucky Theatre
5 minutes' walk
Historic cinema showing classic films and indie features, with a vintage ambiance; check the schedule for special screenings.
WoodSongs Old-Time Radio Hour
WoodSongs Old-Time Radio Hour
10 minutes' walk
Live music show featuring various artists celebrating American roots music; family-friendly atmosphere and unique performances.
Getting around
City Centre
Lexington5 min  ·  400 m
Airports
Blue Grass Airport (LEX)21 min  ·  13.7 km
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Property information and rules
Check-in
from 16:00-23:59
Check-out
until 11 am
Guest Parking
No parking available.
Internet
is available in public areas for free.
Children & extra beds
There are no extra beds provided in a room.  There are no cots provided in a room. 
Pets
Pets are allowed on request.
Number of floors:
15
Number of rooms:
85
FAQs
About 21C Museum Hotel Lexington
What is the check-in and check-out policy at 21C Museum Hotel Lexington?
Check-in is at 16:00 and check-out is at 11:00.
How far is 21C Museum Hotel Lexington from Blue Grass Airport?
The hotel is located 9 km from Blue Grass Airport.
What are the fitness options available at 21C Museum Hotel Lexington?
Guests can enjoy a fitness centre and yoga classes at the hotel.
Does 21C Museum Hotel Lexington provide Wi-Fi access?
Wi-Fi is available for free in guest rooms and public areas.
What on-site dining options does 21C Museum Hotel Lexington feature?
The hotel includes a restaurant and a bar/lounge area.
Which nearby attractions can be found close to 21C Museum Hotel Lexington?
Nearby attractions include the Lexington Convention Center (0.5 km), Hunt-Morgan House (0.5 km), and Rupp Arena (0.5 km).
What room amenities are offered at 21C Museum Hotel Lexington?
Rooms feature air conditioning, a flat-screen TV, a desk, a safety deposit box, and a private bathroom.
Does 21C Museum Hotel Lexington offer business services?
The hotel provides a business centre and meeting rooms for business needs.
What is the closest public transport option to 21C Museum Hotel Lexington?
The Lextran Transit Center bus station is located 0.5 km away.
Is there a bar option available at 21C Museum Hotel Lexington?
Guests can enjoy drinks at the on-site bar/lounge area.
Are there any family-friendly dining options near 21C Museum Hotel Lexington?
Nearby dining options include Dudley's On Short (0.5 km), Zim's Cafe (0.5 km), and Taste of Thai (0.5 km).
Does 21C Museum Hotel Lexington have any special cultural or art programming?
The hotel features temporary art galleries and offers tours or classes about local culture.

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