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From108US$ /night
Check-in
31Dec2025Select date
Check-out
01Jan2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

109 Matthews Lane, Sikeston, Missouri, United States, 63801
-
Near the historic Sikeston Depot
Great
8.1
8.0
/10
3.7
3.6
/5

Comfort Inn & Suites Sikeston I-55 - A pet-friendly hotel with indoor pool, business facilities, and factory outlet proximity

Located within walking distance of VF Factory Outlet mall, this 3-star Sikeston hotel features an indoor heated pool, hot tub, and exercise room. Comfort Inn & Suites Sikeston I-55 provides guest rooms equipped with flat-screen TVs, refrigerators, microwaves, and coffee makers. Each room includes a private bathroom with curved shower rods, plus amenities such as hair dryers and ironing facilities. The property maintains a business center with copy and fax services, along with a public computer offering internet access. Free amenities include wireless high-speed internet, hot breakfast, and parking. Comfort Inn serves travelers with an on-site laundry facility and safe deposit box at the front desk. The hotel sits 2 miles from Malco Sikeston Cinema and Grill, 3 miles from Sikeston Depot Museum & Gallery, and near attractions like Veterans Park and Beggs Family Farm. Cape Girardeau Regional Airport is 28 miles away, while Barkley Regional Airport is 43.5 miles from the property.

Pros

Lambert's Café, known for its 'throwed rolls,' is nearby

Historic downtown Sikeston with retail shops is accessible

Pet-friendly accommodations available

Cons

43.5 miles distance from nearest major airport

Limited dining options within immediate vicinity

“This hotel stands out as a practical choice in Sikeston, particularly for travelers with pets or those needing convenient highway access. The indoor pool and complimentary breakfast add value, though some reports suggest inconsistencies in room cleanliness. I see this as a solid option for budget-conscious stays, especially where pet-friendly accommodations and ample parking are priorities.”
Hotel logo
Isabella MooreSenior Editorial Director at Petfriendlyhotels
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Select your room type

Cozy rooms, spacious suites, and family-friendly homes, all with flexible cancellation policies & special deals
King Room Non-Smoking
2 persons
33 m² 
1 King-size bed
King Suite Non-Smoking
2 persons
33 m² 
1 King-size bed
Queen Room Two Queen Beds Non-Smoking
2 persons
33 m² 
2 King Size Beds
King Room Accessible or Non-Smoking
2 persons
1 King-size bed
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Facilities

Enjoy premium amenities for a relaxing stay with your pet

General

  • Free Wi-Fi
  • Parking
  • Safe deposit box
  • Pets allowed

Children

  • Cots

Spa & Leisure

  • Indoor swimming pool

Bathroom

  • Washing machine

Media

  • AM/FM alarm clock
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Location

109 Matthews Lane, Sikeston, Missouri, United States, 63801
Map view
109 Matthews Lane, Sikeston, Missouri, United States, 63801
Restaurants
El Nopalito Grill
260 m
2600 E Malone Ave
Explore Sikeston
Explore Sikeston
Top Attractions
Activities
Dining
Entertainment
Malco Sikeston Cinema & Grill
10-minute drive
A modern cinema featuring the latest films and a grill menu. Perfect for relaxing movie nights with friends or family.
Sikeston Depot Museum & Gallery
10-minute drive
A historical museum showcasing the rich heritage of Sikeston. Offers guided tours and special exhibits throughout the year.
Boot Heel Golf Club
10-minute drive
A scenic 18-hole golf course that welcomes golfers of all skill levels. Features a pro shop and clubhouse for visitors.
Sikeston Sports Complex
10-minute drive
A multi-sport complex providing fields and courts for various sports. Great for fitness enthusiasts and families alike.
Central Park
10-minute drive
A spacious park offering walking trails, picnic areas, and playgrounds. Ideal for relaxation and outdoor enjoyment.
El Nopalito Grill
4-minute walk
A vibrant Mexican restaurant known for its authentic dishes and friendly atmosphere. Don't miss the enchiladas and fresh salsa.
Malco Sikeston Cinema
10-minute drive
An entertainment venue with state-of-the-art screens and a variety of films. Features a full-service dining experience.
Getting around
City Centre
Sikeston8 min  ·  4.8 km
Airports
Cape Girardeau Regional Airport (CGI)65 min  ·  43.0 km
Barkley Regional Airport (PAH)135 min  ·  89.8 km
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Property information and rules
Check-in
from 14:00-23:59
Check-out
until 11 am
Guest Parking
Private parking is possible on site for free.
Internet
is available in for free.
Breakfast
A buffet breakfast is served at affordable prices. 
Children & extra beds
There are no cots provided in a room. 
Pets
Pets are allowed on request.
Year renovated:
2007
Number of rooms:
64
FAQs
About Comfort Inn & Suites Sikeston I-55
What are the check-in and check-out times at Comfort Inn & Suites Sikeston I-55?
Check-in time is at 14:00 and check-out time is by 11:00.
How far is Cape Girardeau Regional Airport from Comfort Inn & Suites Sikeston I-55?
The hotel is located 45 km from Cape Girardeau Regional Airport.
What are some nearby attractions to Comfort Inn & Suites Sikeston I-55?
Nearby attractions include Bootheel Golf Club (3 km), the historic Sikeston Depot (8 km), and Veterans Park (5 km).
Is parking available at Comfort Inn & Suites Sikeston I-55?
Free private parking is available on-site without the need for reservation.
What kind of breakfast does Comfort Inn & Suites Sikeston I-55 serve?
The hotel offers a complimentary American breakfast daily.
What are the main amenities available at Comfort Inn & Suites Sikeston I-55?
Amenities include free Wi-Fi, an indoor heated swimming pool, a fitness center, and laundry facilities.
What room amenities can guests expect at Comfort Inn & Suites Sikeston I-55?
Rooms include air conditioning, a refrigerator, a microwave, a coffee maker, and a flat-screen TV.
Is there an exercise facility at Comfort Inn & Suites Sikeston I-55?
The hotel features an on-site fitness room for guests.
What dining options are available near Comfort Inn & Suites Sikeston I-55?
Dining options nearby include Lambert's Café and McDonald's, which is located 120 m away.
Does Comfort Inn & Suites Sikeston I-55 have a pool?
The hotel has an indoor heated pool and spa facilities for guest use.
What business services are available at Comfort Inn & Suites Sikeston I-55?
The hotel offers a business center with copy and fax services and a public computer with internet access.
Is there a laundry service at Comfort Inn & Suites Sikeston I-55?
The hotel provides laundry facilities for guest convenience.

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